Obestat

(Meridia, Raductil, Reductil, Vintix, Sibutramine HCL, Ectiva, Aderan, Sibutral, Sibutramina, Sibutraminum, Leptos)

What is Obestat?

Obestat is Sibutramine hydrochloride which is sold under many brand names: Sibumine, Meridia, Obestat, Reductil, Raductil, Reduxade, Ectiva, Leptos, Sibutrex, Sibutrim.

This appetite suppressant is proven effective therapy widely used in combination with dietary plan and exercise to help obese people lose weight and keep it off for good.

Obestat is only suitable for people with a BMI of more than 30 or for people with a BMI of more than 27 who also have other health problems such as diabetes or high blood cholesterol.

Trials showed that Obestat when combined with diet and exercise could reduce weight by 4.5%.

How does Obestat work?

Obestat works by indirectly boosting levels of serotonin and noradrenaline in the brain – two neurotransmitters or chemicals that act on the part of the brain that tells us how hungry or full we feel. When there are more chemicals in this part of the brain, the brain gets more messages to say we feel full. This means we feel more satisfied with less food, so eat smaller amounts and lose weight.

How to take Obestat?

At the start of your treatment Obestat is usually prescribed for a period of four weeks.

The recommended starting dose of Obestat is one 10mg capsule administered once daily with or without food.

If there is inadequate weight loss (ie less than 2kg) after 4 weeks, the dose may be increased to one 15mg capsule once daily provided 10mg was well tolerated. Blood pressure and heart rate changes should be taken into account when deciding to increase the dose.

Doses above 15mg daily are not recommended. In most of the clinical trials, Obestat was given in the morning.

The patient is kept under observation by the doctor in this period of four weeks to check for any signs of weight loss or side effects. Your blood pressure and heart rate is also monitored carefully.

Obestat Side Effects

Obestat is generally well tolerated.

Dry mouth, anorexia, insomnia and constipation are the commonly observed side effects.

Other side effects observed are diarrhea, flatulence, gastroenteritis, peripheral oedema, arthritis, agitation, hypertonia, bronchitis, pruritis and menstrual disorders.

Obestat Precautions

If you are sensitive or allergic to any of the ingredients in Obestat, or if you have a serious eating disorder, you should not take Obestat.

It is not recommended that you take Obestat if you are pregnant or planning to become pregnant, and if you could become pregnant. It is not recommended for nursing mothers.

Obestat is not intended for use in obese children under 18 years as safety and efficacy in this population has not been established.

Obestat is not intended for use in elderly patients over 65 years of age as safety and efficacy in this population has not been established.

Drug Interaction

Obestat should not be taken by people who are taking MAOIs, or monoamine oxidase inhibitors.

It is also not recommended for people who are already taking some other kind of medication for weight loss.
Other medications that may affect the way Obestat works include medicines for coughs, colds, migraines, depression, or pain, or medications that contain narcotics, lithium, tryptophan, or antibiotics.

Obestat Storage

Store Obestat at room temperature, away from heat and moisture in a tight, light-resistant container. Keep this and all medications out of the reach of children.